PROJECTS

CHILD-BRIGHT’s 13 patient-oriented research examine new diagnostic tests, therapies, service models, and technologies that could improve the physical and mental well-being of children with brain-based developmental disabilities. Discover how each research project progressed in 2021-2022 below.  

BRIGHT Beginnings

Projects to optimize brain and developmental outcomes

 
A pregnant woman is placing her hands on her belly, making the shape of a heart

Maternal Hyperoxygenation in Congenital Heart Disease

 

Our preliminary findings suggest that giving mothers supplemental oxygen in the third trimester of pregnancy reduced rates of brain injury for their babies with heart disease. 

 
 
 
A toddler is walking on the grass wearing a tutu and holding a stick

Parent-Centre Evidence-Based Care for Premature Graduates

We are working with parents and families to change how information is collected about children born premature, and to put in place practices to improve their development.

 
 
 

Enhancing Brain Repair with Metformin 

We are evaluating whether metformin enhances motor and cognitive skills in children with cerebral palsy.

 
A photo of the SPORT team

Stimulation for Perinatal Stroke Optimizing Recovery Trajectory

We are well on our way to completing our clinical trial testing whether non-invasive brain stimulation improves function in children with cerebral palsy. 

 

Diagnosis Using Integrated Metabolomics And Genomics In Neurodevelopment

We’ve used advanced genomics and metabolomics to provide a definitive diagnosis to 50% of children with atypical cerebral palsy. 

 
An Indigenous mother tenderly embraces her baby, who is swaddled in a thick blanket.

Prenatal Opioid Exposure and Neonatal Abstinence Syndrome: A Research Project with 13 First Nations Communities in Ontario

We are working with 13 First Nations to better understand the impact of prenatal opioid exposure on children, families, caregivers, and communities. 

 

BRIGHT Supports

Projects to integrate mental health support into care

 
A baby is fast asleep on its mother's shoulder

Optimizing the Management of Pain and Irritability in Children with Severe Neurological Impairment

We’re testing a systematic approach to managing unexplained pain in non-verbal children with severe brain-based developmental disabilities.

 
 
 

Strongest Families Neurodevelopmental Program

We have developed two programs to help parents of neurodiverse children manage challenging behaviours and parental posttraumatic stress. 

 
A toddler is chasing bubbles in a park

Jooay App: Promoting Participation in Leisure

Our Jooay application provides families with easy access to information about appropriate leisure activities in communities across Canada.

 

CHILD-BRIGHT Mega Team:
Treatments to Improve Emotional and Behavioural Self-Regulation

We’re working to improve memory and executive functioning skills in children with brain-based developmental disabilities through cognitive-based video game training.  

 

BRIGHT Futures

Projects to redesign health care services to be more responsive to family needs

 
A newborn is resting in an incubator, with a feeding tube. He is wearing a cute shirt with the words 'Hey there'.

Coached, Coordinated, Enhanced Neonatal Transition (CCENT)

We’ve pioneered new ways to support parents as their newborn transitions from the NICU to home. 

 
 
 

BRIGHT Coaching: A Developmental Coach System to Empower Families of Preschoolers with Developmental Delays

We are evaluating whether our virtual coaching program helps support parents of preschool children with emerging developmental delays as they transition to school entry.

 

READYorNot™ Brain-Based Disabilities Project

We developed and are now evaluating an e-health application designed to help patients and families transition from the pediatric to the adult health care system. 

 

View the progress of our 13 research teams